Using Grignard Reagents - Organic Chemistry
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What is the product of the reaction between magnesium and any alkyl halide, in anhydrous ether?
What is the product of the reaction between magnesium and any alkyl halide, in anhydrous ether?
The reaction between magnesium and an alkyl halide in anhydrous ether results in a Grignard reagent.
An organolithium would result from the same process, but the magnesium would need to be replaced by two equivalents of lithium. Alcohols are products of reactions between a Grignard reagent and a carbonyl.
The reaction between magnesium and an alkyl halide in anhydrous ether results in a Grignard reagent.
An organolithium would result from the same process, but the magnesium would need to be replaced by two equivalents of lithium. Alcohols are products of reactions between a Grignard reagent and a carbonyl.
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What type of reaction would ensue if the ketone compound shown was introduced to 
(a Grignard reagent in water).
What type of reaction would ensue if the ketone compound shown was introduced to
Grignard reagents are known for their ability to readily attack carbonyls at the point of their carbons. However, Grignard reagents do not work in the presence of protic solvents. Rather than reacting with the desired molecule, the Grignard is so unstable that it will readily accept a proton from a protic solvent. The Grignard then becomes inert and no reaction ensues with the desired molecule.
Grignard reagents are known for their ability to readily attack carbonyls at the point of their carbons. However, Grignard reagents do not work in the presence of protic solvents. Rather than reacting with the desired molecule, the Grignard is so unstable that it will readily accept a proton from a protic solvent. The Grignard then becomes inert and no reaction ensues with the desired molecule.
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What reactant(s) is/are needed to drive this reaction?
What reactant(s) is/are needed to drive this reaction?
The carbons on the epoxide compound experience a slightly positive charge. As a result, a Gringard reagent can easily attack the less substituted side of the epoxide to break the ring and to form a six membered carbon chain. 
is used to protonate the negatively charged oxygen atom.
The carbons on the epoxide compound experience a slightly positive charge. As a result, a Gringard reagent can easily attack the less substituted side of the epoxide to break the ring and to form a six membered carbon chain.
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3-bromopropene was treated with 
What is the final major product?
3-bromopropene was treated with
What is the final major product?
Any time we have a Grignard reagent and a primary haloalkane, we will see a substitution reaction, identical to an 
reaction. In this case, the Grignard can easily attack the haloalkane as the bromine leaves to create hexene.
Any time we have a Grignard reagent and a primary haloalkane, we will see a substitution reaction, identical to an
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