Reactions with Nitrogen Compounds - MCAT Biology

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Question

Which of the following statements is true concerning the Hofmann elimination reaction?

Answer

The Hofmann product is the most favored product in a Hofmann elimination reaction. The reaction follows an E2 mechanism, where a quaternary ammonium salt is able to be removed from a hydrocarbon, resulting in an alkene product. This reaction results in the least substituted alkene being the primary product.

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