Properties of Carbohydrates - MCAT Biology

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Question

Which type of bond is created between carbohydrates and the sidechain amine of select asparagine residues in proteins?

Answer

A glycosidic bond covalently joins a carbohydrate molecule to another molecule. An O-glycosidic bond is a covalent linkage between a carbohydrate and a protein, joining a serine or threonine hydroxyl side chain and a sugar (oxygen in the bond yields "O"). An N-glycosidic linkage involves bonding of a carbohydrate and a protein, joining an asparagine side chain amide and a sugar (nitrogen in the bond yields "N"). Thus, N-glycosidic is the correct answer.

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Question

Which of the following statements is true concerning glucose polymers?

Answer

Glucose is the primary carbohydrate absorbed by humans, and exists for its majority of time in the body in ring form. Humans are only capable of digesting alpha linked glucose polymers, and are unable to break down beta linked polymers. As a result, cellulose is incapable of being broken down by humans.

Starch is formed by an -1,4 linkage, while glycogen is formed by an -1,6 linkage. Both of these can be digested, as they do not contain beta linkages.

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Question

Cellulose is a type of carbohydrate used in plants to store glucose. Cellulose cannot be broken down by humans, but is able to be digested by ruminants (cows for example). What is the best explanation for why ruminants are able to digest cellulose?

Answer

Cellulose and other polysaccharides with beta linkages can only be broken down by bacteria. As a result, cows have a symbiotic relationship with bacteria that live in their digestive systems.

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Question

Which carbon in a carbohydrate determines whether a human is capable of digesting it properly?

Answer

Humans are only capable of digesting the "D" isomer of a carbohydrate. The carbon that determines whether a carbohydrate is "D" or "L" is the first chiral carbon in the sugar. If it points to the right, the sugar can be digested by humans.

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