MCAT Biology › Other Muscle Concepts
During muscle contraction, which parts of a sarcomere change in length?
Duchenne Muscular Dystrophy is an X-linked recessive genetic disorder, resulting in the loss of the dystrophin protein. In healthy muscle, dystrophin localizes to the sarcolemma and helps anchor the muscle fiber to the basal lamina. The loss of this protein results in progressive muscle weakness, and eventually death.
In the muscle fibers, the effects of the disease can be exacerbated by auto-immune interference. Weakness of the sarcolemma leads to damage and tears in the membrane. The body’s immune system recognizes the damage and attempts to repair it. However, since the damage exists as a chronic condition, leukocytes begin to present the damaged protein fragments as antigens, stimulating a targeted attack on the damaged parts of the muscle fiber. The attack causes inflammation, fibrosis, and necrosis, further weakening the muscle.
Studies have shown that despite the severe pathology of the muscle fibers, the innervation of the muscle is unaffected.
The “basal lamina” refers to __________.
Which of the following answer options is not a function of the sarcolemma?
Which of the following muscles is an antagonist for the biceps brachii?
What type of muscle cell is quadrangular, and features intercalated disks and multiple nuclei?
Which is not a function of muscle tissue?
The masseter is the most prominent muscle involved in eating food. It is responsible for elevating the jaw during mastication. The temporalis is a muscle located on the outside of the temporal bone. It also elevates the mandible during the chewing of food.
Based on this information, how would you describe the temporalis in relation to the masseter?
Duchenne Muscular Dystrophy is an X-linked recessive genetic disorder, resulting in the loss of the dystrophin protein. In healthy muscle, dystrophin localizes to the sarcolemma and helps anchor the muscle fiber to the basal lamina. The loss of this protein results in progressive muscle weakness, and eventually death.
In the muscle fibers, the effects of the disease can be exacerbated by auto-immune interference. Weakness of the sarcolemma leads to damage and tears in the membrane. The body’s immune system recognizes the damage and attempts to repair it. However, since the damage exists as a chronic condition, leukocytes begin to present the damaged protein fragments as antigens, stimulating a targeted attack on the damaged parts of the muscle fiber. The attack causes inflammation, fibrosis, and necrosis, further weakening the muscle.
Studies have shown that despite the severe pathology of the muscle fibers, the innervation of the muscle is unaffected.
Which of the following would be true of a patient who has Duchenne Muscular Dystrophy?
Which type of muscle has both striations and multiple nuclei?