Immune Proteins and Signals

Practice Questions

MCAT Biology › Immune Proteins and Signals

Questions
7
1

Which toll-like receptor (TLR) recognizes single-stranded RNA?

2

Major histocompatibility complex 1 (MHC-I) presents antigen to which T cell subclass?

3

Naive T cells need to be initially presented with antigen in order to be activated. Which cell type is involved with this initial presentation?

4

The mechanisms of antibody-mediated antigen disposal occur in the what order?

5

The complement system consists of plasma proteins that can directly or indirectly be activated by foreign pathogens. This leads to the induction of a signaling cascade of reactions that occurs on the surface of the pathogens, which leads to different effector functions including opsonization and neutralization. Deficiencies in different components of complement has been linked to an increased susceptibility to autoimmune diseases, including systemic lupus erythematosus (SLE).

Which of the following would be the most likely scenario regarding how a complement deficiency would result in an increased risk of developing autoimmunity?

6

In what part of the body do T cells undergo maturation?

7

Toll like receptors (TLR's) are pattern recognition receptors that recognize specific pathogen-associated molecular patterns (PAMP's) on different pathogens and induce an immune response against the foreign pathogen. Numerous immune cell types express TLR's, including antigen-presenting cells and natural killer cells. TLR's play a critical role in the recognition and induction of the immune response against viruses.

A person that has a decreased inherent ability to detect RNA viruses such as influenza and hepatitis would presumably have a defect in which specific TLR?

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