Help with Vascular and Lymphatic Injuries and Disorders - Human Anatomy and Physiology

Buerger's disease commonly affects small arteries, veins, and nerves, narrowing the channels through which blood flows and causing ischemia (lack of blood supply) to the extremities. Long associated with tobacco exposure, the disease can cause gangrene and lead to amputation of the fingers, toes, hands and feet its most severe form.

Although Pratt's test is not part of Wells' criteria, it is used to screen for DVT's. It involves squeezing the patient's popliteal vein, in the symptomatic leg. A test is considered positive if it causes pain. The other answers listed are part of Wells' criteria.

Sickle cell disease is inherited red blood cell disorders, which cause abnormal hemoglobin to be created. This hemoglobin is known as "hemoglobin S" or sickle hemoglobin. The incorrect structure of the hemoglobin S causes a reduction the red blood cell's ability to travel through blood vessels and transport oxygen to tissues. It also causes the classic "donut" shaped red blood cell to bend due to an amino acid substitution on the periphery of the hemoglobin protein from a hydrophilic one to a hydrophobic one. Anemia is a broad term and can be a result of multiple causes.

An aneurysm is a balloon-like bulge in an artery. Often, these occur in the aorta or arteries in the brain. An aneurysm does not necessarily mean the artery has ruptured. Treatments for aneurysms focus on reducing the chances of the vessel rupturing, such as medications to lower blood pressure or surgery to repair the vessel's wall.

Atherosclerosis is a disease in which plague begins to form in the arteries, which limits the ability of blood to flow through the area. Also the plaque makes the arterial walls less elastic, which increases blood pressure. Plague can build up in any area of the body, although the pulmonary circuit is much less prone to developing atherosclerotic signs. Atherosclerosis can lead to an increased risk of several health problems, including heart attacks and chronic kidney disease.

Kawaski disease is a rare childhood disease that is a form of vasculitis. The walls of blood vessels throughout the body become inflamed with no known cause. It cannot be prevented, but most children recover after a few weeks.

Raynaud's disease is a rare disorder that cause the arteries of the body to have episodes of vasospasms. These vasospasms affect blood flow to the finger and toes most often. The disorder is often managed by minor lifestyle changes.

EBOV is also known as the Ebola virus. It causes a severe hemorrhagic fever that is often fatal in humans and other mammals. EBOV is one of five known viruses within the genus Ebolavirus.

The splenic artery arise from the celiac trunk and gives off branches to the pancreas and stomach. The gastric branches are short gastric and left gastroepiploic. The left gastroepiploic artery anatomoses with the right gastroepiploic artery (a branch of the gastroduodenal artery) and would not be affected by obstruction of the splenic artery. The short gastric artery has no anastomoses and would likely be affected.The inferior and superior mesenteric arteries are not splenic artery branches.

Pernicious anemia is the type of anemia that is caused by lack of vitamin B12. Hemorrhagic anemia is caused by loss of blood. Iron deficiency anemia is caused by low hemoglobin and/or small red blood cells. Hemolytic anemia can result from hemolytic disease of the newborn. Aplastic anemia is when the bone marrow looses its capacity to produce red blood cells.

There are various types of leukemia, all which are caused by a cancerous mutation in the cells of the bone marrow that are producing white blood cells. This causes white cells in circulation to be non functional, yet continue to grow and divide. Myeloma is a type of cancer that also begins in the bone marrow, but affects plasma cells. Lymphoma is a blood cancer of the lymphocytes. Hemophilia is a hereditary bleeding disorder that results from the lack of a clotting factor. Leukopenia is when the bone marrow stops producing white blood cells, causing the body to be more susceptible to infection.