Help with Muscle Proteins and Signals

Practice Questions

Human Anatomy and Physiology › Help with Muscle Proteins and Signals

Questions
8
1

What is the role of creatine phosphokinase (CPK) in skeletal muscle?

2

What protein must undergo a conformational change so that myosin can be attached to actin?

3

What is the role of parvalbumin during a muscle contraction?

4

Tetanic contraction of a muscle fiber results in a substantial increase in the intracellular concentration of which of the following?

5

In malignant hyperthermia, general anesthesia triggers an uncontrolled increase in skeletal muscle metabolism, which causes the body to generate heat faster than it can cool down and use up the body’s store of oxygen. Dantrolene is the medication used to treat this condition, as it will block increases in intracellular calcium. What is the role of calcium in muscle contraction?

6

After the New Year, you decide to make a resolution to exercise more and you enthusiastically wake up early in the cold morning to go for a run. You feel great initially, but ten minutes into your run, you feel a disabling pain in your right calf that forces you to stop and sit on the curb. You feel your calf spasming and note that your toes are pointed downward. You are unable to change this position and think that you have a muscle cramp. A few minutes later the pain subsides and you are able to move your foot again. What molecular deficiency is responsible for this condition?

7

Where within the sarcomere is the ATPase?

8

What is the role of phosphocreatine (PCr) in maintaining ATP concentrations during muscle contraction?

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