Allosteric

Inhibitory

Cofactor

Agonist

Antagonist

The bonds maintaining the shape of the enzyme are broken, and the active site loses its conformation and can no longer bind its proper substrate

Covalent modifications made to the enzyme are disrupted by high temperatures and the enzyme cannot bind its substrate

All substrates are degraded at high temperatures, and therefore there is no reaction to catalyze

The activation energy of the reaction becomes so great that the enzyme cannot overcome the energy, and therefore cannot catalyze reactions

All of these statements describe mechanisms by which heat destroys the catalytic activity of an enzyme

Competitive inhibition

Irreversible inhibition

Uncompetitive inhibition

Non-competitive inhibition

Mixed inhibition

Competitive inhibitor

Non-competitive inhibitor

Uncompetive inhibitor

Allosteric inhibitor

All of these will block the active site of a protein

a lock and key

a gate in a fence

a hole in a wall

a motor in a car

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