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When Jeanie was a child she experienced intense periods of stress and trauma. As an adult, she struggles with severe depression. Despite using multiple prescription anti-depressant medications, Jeanie does not find any one of them to be significantly effective. Which of the following best describes what has happened to Jeanie's brain?
Many women with depression possess an underdeveloped hippocampus—a key component in mood stabilization. Early stress can cause the development of the hippocampus to halt; therefore, the hippocampus is unable to do its job proficiently. Over time, antidepressants may assist with neurogenesis and improve Jeanie's depression but the effects will not be felt as quickly as they might be in someone with an average sized hippocampus.
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The presence of excessive dopamine receptors within the limbic system has been proposed to contribute to positive symptoms of which psychological disorder?
Medical researchers have long such proposed that excessive dopamine in the limbic system--leading to hyperactive, damaged connections between speech and language comprehension as well as hyperactive abnormalities of prefrontal attention--can contribute to positive symptoms of schizophrenia.
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