RNA nucleotides have two hydroxide groups on the sugar, but DNA nucleotides have only one

DNA has uracil, while RNA has thymine

DNA nucleotides are bound by phosphodiester bonds, but RNA nucleotides are bound by glycosidic bonds

RNA nucleotides have five-carbon sugars, while DNA nucleotides have six-carbon sugars

RNA nucleotide bases pair via hydrogen bonds, but DNA nucleotide bases do not

I, III, and V

I, II, and V

I, III, and IV

I, II, and IV

I, II, III, IV, and V

Purine bases will never be found on opposite DNA strands, so they do not have the ability to pair with one another.

The bulky two-ring structure of purines would cause too much hindrance in the inside of the helix.

The functional groups at the end of one purine would not correctly match with the other purine.

Two purines could cause a bump in the DNA, causing problems with transcription and replication.

Only DNA is read in the 5'-to-3' direction

ATP and GTP are nucleic acid derivatives

Only RNA has a hydroxide group attached to the 2' carbon

Both DNA and RNA have nucleotides held together by phosphodiester bonds