GRE Subject Test: Biology › Understanding DNA Sequencing
Traditional Sanger style DNA sequencing relies on a method called chain termination. What type of molecule is used to terminate DNA chains to create molecules of all possible lengths covering the fragment to be sequenced?
Which of the following accounts for the inability of dideoxynucleotide triphosphates to further polymerize in Sanger DNA sequencing?
The determination of the order of the four bases—adenine, thymine, cytosine, and guanine—in a strand of DNA is termed __________.