It blocks the peptidyl transferase reaction on ribosomes

It blocks the translocation reaction on ribosomes

It blocks initiation of RNA chains by binding to RNA polymerase

It blocks the binding of aminoacyl tRNA to the A site of the ribosome

CCA tail

Anticodon loop

D loop

Variable loop

A site

P site

E site

R site

tRNA

mRNA

rRNA

miRNA

Ribosomal proteins are translated in the cytoplasm and transported to the nucleolus. At the same time, rRNA genes are being rapidly transcribed in the nucleolus. rRNA and ribosomal proteins form the 60S and 40S subunits in the nucleolus and are then transported to the cytoplasm for functional ribosome assembly.

Ribosomal proteins are translated in the nucleous and transported to the cytoplasm. At the same time, rRNA genes are being rapidly transcribed in the nucleolus. rRNA and ribosomal proteins form the 60S and 40S subunits in the cytoplasm, where they join to form a functional ribosome.

Ribosomal proteins are translated in the cytoplasm. At the same time, rRNA genes are being rapidly transcribed in the nucleolus. rRNA is transported to the cytoplasm where the rRNA and ribosomal proteins form the 60S and 40S ribosomal subunits.

Ribosomal proteins are translated in the cytoplasm and transported to the nucleolus. At the same time, rRNA genes are being rapidly transcribed in the nucleolus. rRNA and ribosomal proteins form the 50S and 30S subunits in the nucleolus and are then transported to the cytoplasm for functional ribosome assembly.

Ribosomal proteins are translated in the cytoplasm and transported to the nucleolus. At the same time, rRNA genes are being rapidly transcribed in the cytoplasm. rRNA and ribosomal proteins form the 60S and 40S subunits in the cytoplasm.

There are three sites. A site binds aminoacyl-tRNA, P site binds peptidyl-tRNA, E site binds free tRNA before ribosomal exit

There are three sites. A site binds peptidyl-tRNA, P site binds aminoacyl-tRNA, E site binds free tRNA before ribosomal exit

There are three sites. A site binds free tRNA before ribosomal exit, P site binds aminoacyl-tRNA, E site binds peptidyl-tRNA

There are two sites. A site binds free tRNA before ribosomal exit, P site binds aminoacyl-tRNA

There are two sites. A site binds free tRNA before ribosomal exit, P site binds peptidyl-tRNA