Biochemistry › Vmax and Km
What does a small indicate?
There are at least four types of glucose transporter in the body. GLUT1 and GLUT3 are located in most tissues including the brain and the red blood cells. These glucose transporters rapidly take up glucose from the blood but have the lowest value. GLUT2 is commonly found in the liver and the pancreas. GLUT2 has a lower affinity for glucose but has the highest
value. GLUT4 is common in skeletal tissues and in adipose tissues. This transporter is normally not active for uptake unless stimulated by insulin or during exercise.
What might be a consequence of a disease that replaces all GLUT2 with GLUT1?
You are measuring the activity of an enzyme in solution and notice that enzyme activity increases with increasing substrate concentration to a certain point, after which enzyme activity does not increase even if you add more substrate. What is this called and what can be done to increase activity?
There are at least four types of glucose transporter in the body. GLUT1 and GLUT3 are located in most tissues including the brain and the red blood cells. These glucose transporters rapidly take up glucose from the blood but have the lowest value. GLUT2 is commonly found in the liver and the pancreas. GLUT2 has a lower affinity for glucose but has the highest
value. GLUT4 is common in skeletal tissues and in adipose tissues. This transporter is normally not active for uptake unless stimulated by insulin or during exercise.
Sam is performing an experiment and he wants to use the glucose transporter with the lowest value. Which type of glucose transporter should he use?
I. GLUT1
II. GLUT2
III. GLUT3
IV. GLUT4
When an enzyme is in the presence of a competitive inhibitor, which of the following will happen to the enzyme?
Which of these are representations of ?
I.
II.
III. Y-intercept on a Lineweaver-Burk plot
The Michaelis constant, , occurs at what value on an enzyme kinetics graph?