Biochemistry › Synapse Biochemistry
Norepinephrine can be removed from the synaptic cleft via __________.
What serves as the original substrate for serotonin synthesis?
Which of the following is used to degrade catecholamines and serotonin?
How is acetylcholine removed from the synaptic space after acting on its receptors in the postsynaptic membrane?
Which neurotransmitter makes up the majority of neurotransmitters released by chromaffin cells in response to stress?
All of the following are released from storage vesicles upon nerve firing except __________.
Which of the following neurotransmitters do chromaffin cells release?
The absolute refractory period during depolarization is the result of which of these?
Mutations in ion channels can often cause defects in synaptic transmission since propagation of an electrical signal is crucial to proper transmission at the synaptic cleft. You examine mutant mice and identify that the step in synaptic transmission that is defective is at the vesicle release step; that is, the presynaptic cell undergoes a massive depolarization, vesicles in the presynaptic cell dock at the membrane, but the vesicles do not fuse and therefore neurotransmitter is not released into the cleft. Which ion channel is most likely mutated in these animals?
Parkinson disease therapy is difficult because of all the following reasons except: