The enzyme Acyl-Carrier Protein (ACP) plays an important role in the biosynthesis of which of the following?

What is the role of citrate lyase in fatty acid synthesis?

I. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and coenzyme A.

II. It converts ATP to ADP and phosphate.

III. It converts ADP to ATP.

IV. It catalyzes the formation of citrate and coenzyme A from acetyl-CoA and oxaloacetate.

Which of the following are fatty acid synthase components?

I. Malonyl CoA-ACP transacetylase.

II. Beta-ketoacyl synthase.

III. Beta-ketoacyl reductase.

IV. Acetyl CoA-ACP transacetylase.

Note: acyl carrier protein = ACP

In mammals, the enzyme used to synthesize fatty acids is called mammalian fatty acid synthase. It has 7 components that all work together to synthesize a fatty acid chain.

If the DH subunit of the enzyme is mutated and cannot catalyze its proper reaction, which functional group would you expect to see on the resulting carbon chain?

Which of the following is true about major lipoprotein metabolism pathways?

Which of the following are true about fatty acid desaturase and lipid metabolism?

I. The enzyme is located in the endoplasmic reticulum.

II. The enzyme converts saturated fatty acids to unsaturated fatty acids.

III. The enzyme creates double bonds in fatty acid chains.

IV. The enzyme is important in production of arachidonic acid, an inflammatory pathway and cellular signal intermediate.

Malonyl-CoA is a potent inhibitor of carnitine palmitoyl transferase, which facilitates the movement of long-chain fatty acids into the mitochondria for beta-oxidation. This leads to decreased utilization of fatty acids for fuel.

If we wanted to eliminate this effect in a targeted manner, which enzyme would we seek to inhibit?

Which coenzyme is common to reactions catalyzed by pyruvate dehydrogenase and β-hydroxybutyrate dehydrogenase?

What is the role of lecithin-cholesterol acyltransferase (LCAT) in cholesterol metabolism and transport in the body?