Insulin causes a liver cell to convert its glycogen phosphorylase a to glycogen phosphorylase b.

Glucagon stimulates conversion of muscle glycogen phosphorylase b to muscle glycogen phosphorylase a.

Glucose stabilizes the R-state of liver glycogen phosphorylase a.

5’ AMP binds to muscle glycogen phosphorylase b and inhibits it by an allosteric mechanism.

Insulin causes a liver cell to convert its glycogen phosphorylase a to glycogen phosphorylase b.

Glucagon stimulates conversion of muscle glycogen phosphorylase b to muscle glycogen phosphorylase a.

Glucose stabilizes the R-state of liver glycogen phosphorylase a.

5’ AMP binds to muscle glycogen phosphorylase b and inhibits it by an allosteric mechanism.

Breakdown of glycogen in muscle produces mostly glucose, which is released into the blood.

Glycogen provides a way to store energy in tissues that consume large amounts of energy when an organism is active.

Glycogen provides a reservoir of glucose molecules that can be used to replenish the blood with glucose when food is not available.

Both the synthesis and the breakdown of glycogen are regulated.

Breakdown of glycogen in muscle produces mostly glucose, which is released into the blood.

Glycogen provides a way to store energy in tissues that consume large amounts of energy when an organism is active.

Glycogen provides a reservoir of glucose molecules that can be used to replenish the blood with glucose when food is not available.

Both the synthesis and the breakdown of glycogen are regulated.

Skeletal muscle

Fat

Brain

Liver

Skeletal muscle

Fat

Brain

Liver

Glycogenolysis

Protein synthesis

Gluconeogenesis

DNA polymerization

Glycogenolysis

Protein synthesis

Gluconeogenesis

DNA polymerization

I, II, and III

I and IV

II and III

II, III, and IV

I and II

I, II, and III

I and IV

II and III

II, III, and IV

I and II