Understanding Antibodies and Antigens

Practice Questions

AP Biology › Understanding Antibodies and Antigens

Questions
8
1

Which of the following statements describes the primary role of major histocompatibility complex (MHC) class I molecules?

2

Major histocompatibility molecules (MHC) are critical for the functioning of the immune system. These proteins are utilized allow for communication between the immune system and the cells. MHC I are utilized to show which cells are in fact part of the body and which are foreign. MHC II are utilized to show the immune system when there is an intruder.

MHC I molecules are derived from chromosome 6. On chromosome 6, there is a specific gene that encodes for the molecule. On the gene, there are 3 locus (A, B, C) which allows for variability in the binding site of the MHC I molecule. The MHC gene is co-dominance and therefore adds to its diversity. During development, the gene is transcribed into MHC I molecules. However, some of these are broken down and react with a particular MHC I molecule. The reaction allows for the MHC I molecule to surface onto the cellular membrane and to self-identify the protein for the cytotoxic T-cell.

After translation, MHC II molecules are transported to the endosome. When a pathogen binds to the proper MHC II binding site, these molecules are then presented to T-Helper cells. In comparison, MHC I molecules interact with endogenous antigens whereas MHC II molecules interact with exogenous antigens.

Based on the passage, where is the interaction between the MHC I molecule and the particular antigen occur?

I. Endoplasmic reticulum

II. Endosome

III. Cytoplasm

3

Major histocompatibility molecules (MHC) are critical for the functioning of the immune system. These proteins are utilized allow for communication between the immune system and the cells. MHC I are utilized to show which cells are in fact part of the body and which are foreign. MHC II are utilized to show the immune system when there is an intruder.

MHC I molecules are derived from chromosome 6. On chromosome 6, there is a specific gene that encodes for the molecule. On the gene, there are 3 locus (A, B, C) which allows for variability in the binding site of the MHC I molecule. The MHC gene is co-dominance and therefore adds to its diversity. During development, the gene is transcribed into MHC I molecules. However, some of these are broken down and react with a particular MHC I molecule. The reaction allows for the MHC I molecule to surface onto the cellular membrane and to self-identify the protein for the cytotoxic T-cell.

After translation, MHC II molecules are transported to the endosome. When a pathogen binds to the proper MHC II binding site, these molecules are then presented to T-Helper cells. In comparison, MHC I molecules interact with endogenous antigens whereas MHC II molecules interact with exogenous antigens.

Based on the passage, where is the interaction between the MHC II molecule and the particular antigen occur?

I. Endoplasmic reticulum

II. Endosome

III. Cytoplasm

4

What happens antibodies for a specific antigen when that antigen is presented in the body?

5

Major histocompatibility molecules (MHC) are critical for the functioning of the immune system. These proteins are utilized allow for communication between the immune system and the cells. MHC I are utilized to show which cells are in fact part of the body and which are foreign. MHC II are utilized to show the immune system when there is an intruder.

MHC I molecules are derived from chromosome 6. On chromosome 6, there is a specific gene that encodes for the molecule. On the gene, there are 3 locus (A, B, C) which allows for variability in the binding site of the MHC I molecule. The MHC gene is co-dominance and therefore adds to its diversity. During development, the gene is transcribed into MHC I molecules. However, some of these are broken down and react with a particular MHC I molecule. The reaction allows for the MHC I molecule to surface onto the cellular membrane and to self-identify the protein for the cytotoxic T-cell.

After translation, MHC II molecules are transported to the endosome. When a pathogen binds to the proper MHC II binding site, these molecules are then presented to T-Helper cells. In comparison, MHC I molecules interact with endogenous antigens whereas MHC II molecules interact with exogenous antigens.

Based on the passage, which MHC molecule and T-cell is targeted post-organ transplant to avoid rejection of the organ?

6

Which of the following correctly describes the relationship between an antigen and an antibody?

7

An antibody can be best classified as which of the following?

8

The chemical reaction in the immune system that protects the body from pathogens is a result of antibodies created by which of the following?

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