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Hellenistic rule over the former Persian Empire was overthrown by the rise of the __________.
Hellenistic rule over the former Persian Empire began in the late fourth century BCE, with the successful conquests of Alexander the Great. However, Hellenistic rule over Persia did not last long. The Parthian Empire (who would become longtime rivals to the Roman Empire) emerged and overthrew the Hellenistic rulers of Persia in the third century BCE.
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